UK’s Largest Pharmaceutical Cleanroom
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The Customer
A leading global supplier of drug delivery devices for injectable and inhaled products.
The Brief
The brief was to design, supply and install bespoke HVAC, mechanical and electrical services to a new purpose-built cleanroom facility with a total volume of 18,000 m³. The room required a minimum of 60 m³/s of air to meet the design specification for validation.
The facility (now the UK’s largest Pharmaceutical Cleanroom) was to meet ISO class 7 operational for 50 weeks of the year maintaining a tight temperature control of 21OC (+/- 3 OC) & humidity of 45% RH (+/- 15%) with a positive pressure of 30 pa cascading through the adjoining lobby areas with a maintained differential of 15 pa.
Part of the design challenge on this project was the uneven heat loads across the facility combined with a vast area that requires a minimum of 12 air changes per hour.
In addition to the facility’s air handling, JD Cooling & JD Power were also employed through the main contractor to supply and install a new process water system and full electrical installation package.
We are delighted to have had the opportunity to work closely with our customer on what is now the ‘largest pharmaceutical cleanroom’ in the UK. This project is an installation that we are extremely proud of and one that the end-user is very happy with.
MIKE GOULD
HVAC Manager, JD Cooling
The Solution
Heating, Ventilation and Air Conditioning
- 900 kW multi-circuit chiller serving the AHUs
- 650 kW adiabatic dry air cooler serving the process
- Three multi-function close control AHUs
- Amenities VRF and heat recovery systems
- Cleanroom air distribution socks and ductwork
- Acoustic plant packages
- Both mechanical and electrical services
- Information and operation validation
Electrical Installation
As part of the scheme, the client required new LV distribution to their new cleanroom, all electrical services, lighting and fire alarm systems.
The power requirement was very high and needed to be designed to be as efficient and economical as a building requiring potentially 5000 amps of power could be.
The challenge was to supply this amount of power along with the potential to expand the electrical supply in the future possibly quite significantly.
The requirement for this amount of power and the building design/usage dictated the use of two mains transformers provided by a local power distribution company, two low voltage mains panels fitted with power factor correction, and numerous sub-panels, distribution boards, and equipment control panels installed by JD Power Systems.
Technical Specifications
Performance Specification – AHU (3) – Custom Built
Design Ambient
+32°c
Design Room
21 °C / 45% RH
Supply Air Volume
21m³/s per AHU
Cooling
300kW per AHU on chilled water
Heating
Indirect gas fired heating with auxiliary electric heating
Fan
Inverter driven EC plug fan (2 per AHU)
Humidification
Steam electrode supplied with RO water
Filtration
G4, F8 & Terminal H14 (pre, bag & Terminal Hepa)
Performance Specification – Chiller (1) – Special Built
Cooling Capacity
900kW
Design Ambient
+32°c
Chilled Water
Supply: +6°c / Return: +12°c
Capacity Steps
9 stages of capacity cooling
Refrigerant
R410a
EEV
Electronic
Modification
Full Acoustic enclosure fitted
Performance Specification – Process Cooler (1) – Special Built
Cooling Capacity
650kW
Type
Adiabatic dry air cooler
Design Ambient
+32°c
Fans
EC
Refrigerant
None
Modification
Full Acoustic enclosure fitted
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